retina saturation retinal oximetry
Conditions
Interventions
The purpose of a retinal oximeter is the measure the relative oxygen saturation
in the retinal vessels. Therefore, measuring oxygen saturation in different
oxygen conditions (normoxia / hyperoxia) i
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Participants with an age between 18 - 35 years
Exclusion criteria
Exclusion criteria: • Subjects will be excluded in case of pathological findings during the ophthalmologic examination incl. ocular opacity • Subjects will be excluded if refractive error is lagers than +/- 6.00 dioptres and / or a cylinder of +/- 1.50 dioptres • Subjects will be excluded in case of any ocular diseases in their history or a familial history of glaucoma. • Subjects with any systemic disease, which could affect the eye or oxygen levels such as diabetes, respiratory- and cardiovascular disease are excluded. • Subjects are excluded if they smoke
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ODR will be determined in three different situations (Sitting, supine and hyperoxic) to make a comparison between the CORIMAP prototype camera and the Oxymap T1. The ODR is inversely linear related to the oxygen saturation. Therefore, the oxygen saturation can be determined in the retinal vessels. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary study parameter is the measurements of the prototype CORIMAP camera and Oxymap T1 of the diameter of the vessels of the retina in both normoxia and hyperoxia. | — |
Countries
Netherlands
Outcome results
None listed