autoimmune disease glutenintolerance
Conditions
Interventions
The novel, validated, rapid point of contact (POC) tests to determine CD
specific blood antibodies against the enzyme tissue transglutaminase2 (TG2A) in
children aged 12 months-4 years visiting the
Coeliac disease
gluten
paediatric
youth health care centre
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: age 12 months to 4 years, not previously screened for CD, not diagnosed with CD, not on a GFD, parents have a sufficient knowledge of Dutch language, informed consent
Exclusion criteria
Exclusion criteria: insufficient knowledge of Dutch language and/or inability to understand the information provided, children on a GFD children who are already diagnosed with coeliac disease. no informed consent,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To establish the feasibility, effectiveness and costs of mass screening of CD in children attending the YHCCs in a well described region in the Netherlands, using a POC test for TG2A determination. Comparison with outcome of current healthcare. | — |
Secondary
| Measure | Time frame |
|---|---|
| To establish the acceptance of the mass screening by the Dutch population and the ethical aspects involved | — |
Countries
The Netherlands
Outcome results
None listed