The effect of "Spherical Nucleic Acids" on gene expression in skin biopsies of volunteers with psoriasis.

The effect of "Spherical Nucleic Acids" on gene expression in skin biopsies of volunteers with psoriasis. - The effect of SNA on gene expression in psoriasis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43337

Enrollment

Registered

2016-10-31

Start date

2016-12-19

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psoriasis

Interventions

biopsies

psoriasis

skin

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Patients with moderate to severe psoriasis

Exclusion criteria

Exclusion criteria: Volunteers undergoing UV/light therapy or taking systemic drugs such as cyclosporin A or methotrexate Volunteers using local topical corticosteroids Volunteers developing psoriasis at wound sites (Köbner phenomenon)

Design outcomes

Primary

Measure	Time frame
Down regulation of TNF* gene by XCUR17	—

Secondary

Measure	Time frame
Other genes affected by XCUR17	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)