Fatigue in patients with primary Sjögren*s syndrome

Fatigue in patients with primary Sjögren*s syndrome - Fatigue-pSS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43326

Enrollment

Registered

2016-07-11

Start date

2016-09-20

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sjögren's syndrome

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Both patients and control subjects: > Age: 18-65 years > Adequate hand function that allows subjects to utilize the force transducer > Patients: diagnosed with pSS according to AECG and/or ACR-EULAR classification criteria

Exclusion criteria

Exclusion criteria: Both patients and control subjects: > Drug or alcohol addicition > Neurologic condition unrelated to pSS > Psychiatric disorder > Other condition influencing fatigue > Medication influencing fatigue or the immune system > fMRI related exclusion criteria

Design outcomes

Primary

Measure	Time frame
The most important parameters are the maximal FDI muscle force, force decline during the fatiguing task, muscle activation during the fatiguing task, questionnaire scores, and the changes in cortical activation during the fatiguing task (functional MRI data).	—

Secondary

Measure	Time frame
Electromyographic activity of the FDI muscle during the motor tasks	—

Countries

Netherlands

Outcome results