obesity overweight
Conditions
Interventions
Every subject receives two treatments on two different days with at least one
week in between, following a randomized cross-over design. On the test day, the
subjects will arrive in fasted state and
same oil droplet size as intervention and
in presence of *empty* encapsulation matrix). Two hours after the intervention
yoghurt, once the lipid will be released to the distal small intestine, ad
l
encapsulation
ileal brake
slow release
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: BMI (25-30), healthy (Based on medical history and previous examination, no serious gastrointestinal complaints can be defined)
Exclusion criteria
Exclusion criteria: milk allergy/intollerance, dieting, pregnancy/lactation, excessive alcohol consumption, intention to stop smoking, severe disease, major abdominal surgery, abnormal eating behaviour
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate whether encapsulation of lipids decreases ad libitum food intake compared to non-encapsulated lipids in a formulation with equal nutrients (control). | — |
Secondary
| Measure | Time frame |
|---|---|
| - Feelings of satiety (VAS scores) - Occurance and severity of GI symptoms (VAS scores) - Yoghurt type specific differences in food intake, satiety and adverse GI symptoms | — |
Countries
The Netherlands
Outcome results
None listed