Periodontitis and Rreumatoid arthritis- association, dual treatment and resolution study

Periodontitis and Rreumatoid arthritis- association, dual treatment and resolution study - PARASOLVE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43308

Enrollment

100

Registered

2016-07-20

Start date

2017-05-04

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

destructive inflammation of periodontal ttisues periodontitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: (N

Exclusion criteria

Exclusion criteria: active infectious or other inflammatory disease

Design outcomes

Primary

Measure	Time frame
the effect of resolvin E1 on T helper 17 activation and pro-inflammatory cytokines in gingival, blood and synovial tissue from RA patients and on gingival tissue and blood of patients at risk for RA.	—

Secondary

Measure	Time frame
Presence, isotype and fine specificity of ACPA, arginin control antibodies and anti-P.gingivalis antibodies, bacterial cell numbers and products and key inflammatory cytokines and chemokines in gingival tissue and synovial tissue of patients with PD and RA and patients with PD at risk for RA.	—

Countries

Netherlands

Outcome results