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Ki-67 and cytokeratin 16 expression in several lesion types of hidradenitis suppurativa compared to keratosis pilaris and psoriasis inversa. A pilot investigation

Ki-67 and cytokeratin 16 expression in several lesion types of hidradenitis suppurativa compared to keratosis pilaris and psoriasis inversa. A pilot investigation - Pilot: Ki-67 and CK16 in HS, keratosis pilaris and psoriasis inversa

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON43302
Enrollment
50
Registered
2016-12-22
Start date
2017-03-03
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acne ectopica acne inversa hidradenitis suppurativa

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy controls: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Subjects are not affected with HS, psoriasis inversa and keratosis pilaris. - Subjects do not have another skin disease located at the armpits or groins - Age 18-65 years * Patients with psoriasis inversa and keratosis pilaris: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Subjects are not affected with HS - Subjects do not have another skin disease located at the site of the affected skin. - Age 18-65 years;Patients with HS that have pseudo-comedone lesions In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Subjects are not affected with psoriasis inversa. Also, subjects are not affected with keratosis pilaris at the site of pseudo-comedones. - Subjects do not have another skin disease located at the site of the affected skin. - Age 18-65 years;Patients with HS with inflammatory nodules via left-over material from STEEP-surgery - Subjects are not affected with psoriasis inversa. Also, subjects are not affected with keratosis pilaris at the surgical site. - subjects do not have other skin manifestations at the site of STEEP-surgery, particularly no psoriasis inversa and keratosis pilaris. - Age 18-65 years

Exclusion criteria

Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Subjects who have not given informed consent - Subjects 65 years old

Design outcomes

Primary

MeasureTime frame
To investigate the expression of cytokeratin 16 and ki-67 in the different segments of the FPSU of all the above mentioned conditions

Secondary

MeasureTime frame
N.A.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)