The MPAC-study: validating craniocaudal tumor extension on MRI with histoPAthology in patients with Cervical cancer

The MPAC-study: validating craniocaudal tumor extension on MRI with histoPAthology in patients with Cervical cancer - De MPAC-study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43285

Enrollment

Registered

2017-04-18

Start date

2013-05-17

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer uterine cervical carcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with a carcinoma of the cervix for whom a Wertheim surgical procedure is planned. They must be older than 18 years of age and have a WHO status of 0 or 1.

Exclusion criteria

Exclusion criteria: Exclusioncirteria are MRI related. Patients with claustrophobia, a pacemaker, medicine pump, neurostimulator, cochlear implants, other metal implants in the pelvis wich would disturb the image. In some cases surgical clips in the brain are contra-indicated, this will be evaluated conform standard protocol. Patients with a GFR

Design outcomes

Primary

Measure	Time frame
Craniocaudal primary tumor extension in direction of the uterine fundus on T2 weighted 3T MRI enforced with DWI/DCE compared to histopathology.	—

Secondary

Measure	Time frame
To establish the correlation of T2 weighted MRI enforced with DCE and DWI with the microscopic tumor extent in uterine cervical cancer in uterus and parametrium.	—

Countries

Netherlands

Outcome results