abdominal wall pain entrapment neuropathy
Conditions
Interventions
Sponsors
Maxima Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: ACNES group: - Diagnosis of ACNES based upon 3 of 4 of the following characteristics: - Sensory disturbances at triggerpoint site - Positive Carnet*s sign at triggerpoint site - Positive Pinch sign at triggerpoint site - Positive modified rectus sheath block (>50% pain reduction) - Unilateral - Subject is at least 18 years old but younger than 55 - Subject is able and willing to comply with the follow-up schedule and protocol - Subject is able to provide written informed consent;Healthy controls: - Subject is at least 18 years old but younger than 55 - Subject is able and willing to comply with the follow-up schedule and protocol - Subject is able to provide written informed consent
Exclusion criteria
Exclusion criteria: - Female subject of childbearing potential is pregnant - Significant comorbidity - Previous abdominal open surgery with significant scars - Skin lesions at target sites - (Other) pain syndromes such as fibromyalgia, carpal tunnel syndrome, etc. - Neurological disorders associated with sensory loss, e.g. diabetic neuropathy, MS, etc. - Attention deficit disorders - Opioid use or pain treatment regimen that can*t be temporarily interrupted;Only for healthy controls: (history of) ACNES
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant differences between ACNES patients, healthy volunteers and database reference values on different modalities of the standardized QST protocol of the German Research Network on Neuropathic Pain (DFNS). This includes Cold/Warm detection threshold, Cold/Heat pain threshold, Pin prick sensitivity, Wind-up, and pressure pain thresholds. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoint is differences in therapy outcomes in the ACNES group by sensory profile. | — |
Countries
The Netherlands
Outcome results
None listed