depression major depressive disorder
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Age 60 years or over. - Suffering from clinically relevant depressive symptoms defined as a score of 16 or more on the Center for Epidemiological Studies Depression Scale (CES-D) (Radloff, 1977; Eaton et al, 2004). - Having met the criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM-5) for a major depressive disorder (MDD) within the past 12 months (but no current MDD) as established with the Mini International Neuropsychiatric Interview (version 5.0). - Right handedness. - Giving informed consent after oral and written information about the study
Exclusion criteria
Exclusion criteria: - Insufficient command of the Dutch language. - Not capable of daily neurofeedback training. - Major psychiatric comorbidity other than an affective disorder (encompassing mood-, anxiety or somatoform disorders). - An established (or suspected) diagnosis of dementia or a neurodegenerative disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variance in depressive symptoms explained by changes in NF induced frontal alpha lateralization within individuals. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Feasibility and patient burden of both NF training and data collection from a patient perspective - Compliance to NF training and study procedures - Psychopathology at baseline, and after 4, 8 and 12 weeks. | — |
Countries
Netherlands
Outcome results
None listed