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Intraoperative control of maxillary malignancy resection with cone-beam computed tomography

Intraoperative control of maxillary malignancy resection with cone-beam computed tomography - Image guided maxillectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON43222
Enrollment
6
Registered
2017-01-03
Start date
2017-03-07
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

maxillary cancer upper jaw malignant tumor

Interventions

Preoperative imaging with MRI of the maxilla will be obtained for all patients. Segmentation of the resection area will be then performed on the coronal and transverse sections of the MRI scans of e
cone-beam computed tomograply
maxillary cancer
maxillectomy

Sponsors

Antoni van Leeuwenhoek Ziekenhuis
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: * Primary tumours of the maxilla (T1-T4a for non-melanomas and T3-T4a for melanomas), confirmed by biopsy. Recurrent cases are also eligible. * Any lymph node status * M0 status * Treatment plan approved by the multidisciplinary Head and Neck oncology meeting of the AvL * Age over 18-years old * No contraindications to general anesthesia * Informed consent, written and signed

Exclusion criteria

Exclusion criteria: * Unresectable tumours of the maxillary sinus * Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol * Pregnancy

Design outcomes

Primary

MeasureTime frame
* Technical feasibility of determining and marking of the planned treatment volume in the preoperative MRI. * Technical feasibility of obtaining intraoperative CBCT of the maxilla. * Assessment of the quality of matching (CBCT and MRI) by using the *Sorensen- Dice coefficient* and *Hausdorff distance*. * Rate of complete resection achieved compared to the preoperatively planned treatment volume.

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)