Neurological, visual and neurocognitive performance in perinatally HIV-1- infected patients as compared to healthy controls.* NOVICE II Follow up study

Neurological, visual and neurocognitive performance in perinatally HIV-1- infected patients as compared to healthy controls.* NOVICE II Follow up study - NOVICE II

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43220

Enrollment

Registered

2016-10-28

Start date

2017-04-24

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain disease neurologic and neurocognitive impairment

Interventions

neurodevelopment

neurology

perinatally hiv infected patients

Eligibility

Age

2 Years to 64 Years

Inclusion criteria

Inclusion criteria: * Cases: Perinatally infected with hiv * Age: older than 8 years of age

Exclusion criteria

Exclusion criteria: * Intracranial malignancy, history of traumatic brain injury with loss of consciousness > 30 minutes * Severe psychiatric disorders * MRI contra-indications (e.g. implanted active devices such as pacemakers or medication pumps, or metal splinters in eye, brain or lungs, claustrophobia. Dental braces are allowed.)

Design outcomes

Primary

Measure	Time frame
Main endpoints are alterations in neurocognitive performance over time, alterations in neuroimaging parameters and ophthalmological measurements over time, comparing HIV positive cases to healthy controls. CSF and blood parameters will be measured and correlated to the results of the above mentioned tests.	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)