Non invasive investigation of the underlying cause of differences in metabolic capacity along the length of the tibialis anterior muscle using Magnetic Resonance

Non invasive investigation of the underlying cause of differences in metabolic capacity along the length of the tibialis anterior muscle using Magnetic Resonance - Metabolic capacity in the tibilias anterior

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43213

Enrollment

Registered

2017-03-20

Start date

2017-06-15

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N/A

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - healthy - male - Age between 18-35 years - BMI between 19 and 25 kg/m2 - MR eligibility; verified using a questionnaire

Exclusion criteria

Exclusion criteria: - MR ineligibility; verified using a questionnaire -- inability to lay supine for 90 minutes

Design outcomes

Primary

Measure	Time frame
The main study parameters are the exercise PCr decline and post exercise recovery, potential splitting of Pi peaks, end-exercise pH, muscle perfusion via MRI and NIRS.	—

Secondary

Measure	Time frame
A secondary study parameter is the local strain measured with ultrasound.	—

Countries

Netherlands

Outcome results