Imaging of extracranial carotid aneurysms

Imaging of extracranial carotid aneurysms - ECAA imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43210

Enrollment

Registered

2016-09-13

Start date

2017-02-14

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dilatation of the extracranial carotid artery expansion of the neck artery

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Dutch patient registered in the carotid aneurysm registry Willingness and ability to participate in all scheduled procedures outlined in the protocol. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Subject registered in the CAR that have undergone surgical or endovascular treatment of the ECAA. 2. Patients with contraindications for CTA such as: 1) severe renal insufficiency (GFR

Design outcomes

Primary

Measure	Time frame
Observational study: differences in diameter measurements using 3T MRI and CTA will be assed.	—

Secondary

Measure	Time frame
- The inter-rater reliability and intra-observer agreement of volume measurement in ECAA using CTA with 3D reconstruction at baseline and 1 year after baseline measured by two independent observers blinded for previous imaging. - Aneurysm diameter growth (defined as at least 3mm growth in largest diameter of the aneurysm) on 3T MRI between baseline and 1 year after baseline measured by two independent observers blinded for previous imaging. - Degree of gadolium enhancement in the ECAA wall on 3T MRI (categorized into no, moderate or severe enhancements). 3T MRI will be read by two independent observers blinded for patient data and previous imaging. - Correlation between gadolium enhancement and aneurysm growth on 3T MRI. - Prevalence of white matter abnormalities on 3T MRI.	—

Measure

Time frame

- The inter-rater reliability and intra-observer agreement of volume measurement in ECAA using CTA with 3D reconstruction at baseline and 1 year after baseline measured by two independent observers blinded for previous imaging. - Aneurysm diameter growth (defined as at least 3mm growth in largest diameter of the aneurysm) on 3T MRI between baseline and 1 year after baseline measured by two independent observers blinded for previous imaging. - Degree of gadolium enhancement in the ECAA wall on 3T MRI (categorized into no, moderate or severe enhancements). 3T MRI will be read by two independent observers blinded for patient data and previous imaging. - Correlation between gadolium enhancement and aneurysm growth on 3T MRI. - Prevalence of white matter abnormalities on 3T MRI.

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Countries

Netherlands

Outcome results