Invasive breast cancer
Conditions
Interventions
On the day of the marker implantation, a supine contrast-enhanced (CE) MRI is
acquired.
After the implantation procedure, a CT without contrast agent is acquired.
Breast cancer
Electromagnetism
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: • Patients with an invasive breast carcinoma, visible on prone CE-MRI. • Patients who are scheduled for single-seed RSL. • A signed informed consent. • Patients >= 18 years old.
Exclusion criteria
Exclusion criteria: • Contraindication for MRI in supine position or CT. • Contraindication for gadolinium contrast administration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the study is the accuracy of the supine MRI-guided navigated tumor marker implantation. The accuracy is defined as the difference between planned marker location on supine MRI and actual marker location as seen on CT which is acquired after the implantation procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome of the study is the variability in target volume delineations on pre-operative supine CT with that of registered supine CT-MR scans. The variability is defined as the difference in standard deviation on the surface distance maps between the delineations made on CT only compared to that of registered MR-CT. | — |
Countries
The Netherlands
Outcome results
None listed