Effect of administration of single dose Histidine-Tryptophane-Ketoglutarate (HTK) cardioplegia solution on serum sodium concentration, osmolarity and acid-base balance.

Effect of administration of single dose Histidine-Tryptophane-Ketoglutarate (HTK) cardioplegia solution on serum sodium concentration, osmolarity and acid-base balance. - Effect of HTK on serum sodium concentration, osmolarity.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON43165

Enrollment

Registered

2017-04-10

Start date

2017-12-12

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

electrolytstoornissen en stoornissen in osmolariteit en het zuur-base evenwicht hyponatriemia low sodium concentration

Interventions

Cardioplegia

Histidine-Tryptophane-Ketoglucorate

osmolarity

sodium concentration

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: * patients undergoing non emergency cardiothoracic surgery where HTK solution or St Thomas' cardioplegia solution will be used for myocardial protection * Older than 18 years

Exclusion criteria

Exclusion criteria: * Emergency procedures * Younger than 18 years * Allergy to HTK or St Thomas' cardioplegie * Serum sodium abnormalities before surgery

Design outcomes

Primary

Measure	Time frame
Serum sodium concentration Osmolarity Acid-base balance	—

Secondary

Measure	Time frame
Acid-base balance	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)