gezonde veroudering getting older healthy ageing
Conditions
Interventions
We will treat participants with a Neuroelectrics Starstim tCS, a class IIa
device according to the classification in the Council Directive 93/42/CEE for
medical devices. TDCS will be delivered throu
the cathode electrode will be placed on
the right supraorbital region. Impedance is checked before and during
stimulation to ensure good contact quality of the sponges with the scalp. The
stimulati
ageing
motor learning
tDCS
Sponsors
Universiteit van Twente
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: * Age 62 * 75 or 18 * 30 years * Right-handed, to be confirmed by using the Edinburgh handedness inventory (Oldfield, 1971). * Good vision (on 1 meter distance), glasses are allowed
Exclusion criteria
Exclusion criteria: * History of skin diseases that could result in irritation of the skin underneath the electrodes * History of epilepsy or a known case of epilepsy in a first degree relative * Metallic implants in the brain * Presence of cardiac pacemakers, implanted heart rhythm monitor, implanted defibrillator, cochlear implant or implanted brain electrodes * Presence of severe or frequent headache * Use of medication that alters the motor cortex excitability * Use of medication that, according to the product information, can increase the chance of seizures. * Use of any illegal drugs in the last month (relying on self-report) * Pregnancy * Had spinal surgery or have drains in their spinal cord or ventricles * Other neurological disorders * A history of cardiac conditions that interfere with physical load * Severe depression * A score on the Montreal Cognitive Assessment (MoCA) of 22 or lower, indicating mild cognitive impairment (Nasreddine et al., 2005). This tool has been extensively validated (e.g., Freitas, Simões, Alves, & Santana, 2013). YA will not be administered this questionnaire. See appendices for full questionnaire. * Severe motor problems or limitations in using the fingers or arms, chronic joint pain, arthritis or rheumatism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Participants will perform a sequence-learning task, performance on this task will provide the main outcome parameters. The participant uses a response box to learn to tap a 5-element sequence as many times as possible in a 3 minute time period. All right-hand fingers excluding the thumb are used. In total, 8 blocks of 3 minutes tapping are included. In the fixed-sequence blocks (Baseline Sequence, and practice blocks 1 to 5), a fixed sequence is displayed continuously on the computer screen. In the random-sequence blocks (1 block before and 1 block after the fixed-sequence blocks), a new random sequence is to be performed after every sequence performance. The main study parameter will be the number of sequences performed correctly, relative to the baseline sequence block, during each practice block. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary study parameter will be the number of random sequences performed correctly in the post-test random sequence block, relative to the baseline random sequence block. | — |
Countries
The Netherlands
Outcome results
None listed