The longitudinal effects of repetitive tDCS on cigarette consumption: An ecological momentary assessment (EMA) study

The longitudinal effects of repetitive tDCS on cigarette consumption: An ecological momentary assessment (EMA) study - Effects of tDCS on cigarette consumption

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON43108

Enrollment

Registered

2016-10-06

Start date

2016-09-04

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Verslaving Nicotine addiction Tobacco use

Interventions

One group receives bilateral tDCS (left cathodal/right anodal) over the DLPFC. The stimulation will take place two times daily for 13 minutes with a rest interval of 20 minutes for five consecutive

ERPs

Smoking

tDCS

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Between 18 and 65 years old - Currently smoking 10 or more cigarettes a day - The ability to speak, read, and write in Dutch at an eight-grade literacy level

Exclusion criteria

Exclusion criteria: - The current abuse of a substance other than nicotine or caffeine - History of neurological or psychiatric disorders - Any contraindication for electrical brain stimulation procedures such as electronic implants or metal implants - Pregnancy or breast-feeding - In the process of stopping smoking

Design outcomes

Primary

Measure	Time frame
Mean number of smoked cigarettes a daythree months after tDCS treatment, as measured by means of EMA for one week Mean craving a day three months after tDCS treatment, as measured by means of EMA for one week Behavioral and electrophysiological responses to risk-taking and inhibitory control directly before and after the tDCS treatment week. These measures of inhibitory control can be assessed during NoGo trials on the Go/NoGo task. Mean number of pumps on the BART task will represent risk-taking. Positive and negative feedback during the BART task can be used to study electrophysiological responses (See paragraph 8.3 page 17 of protocol). Number of cigarettes (and craving) per day starting on the first tDCS day until one week after the last tDCS intervention (total of 14 days) to study the course of cigarette consumption during and after tDCS.	—

Measure

Time frame

Mean number of smoked cigarettes a daythree months after tDCS treatment, as measured by means of EMA for one week Mean craving a day three months after tDCS treatment, as measured by means of EMA for one week Behavioral and electrophysiological responses to risk-taking and inhibitory control directly before and after the tDCS treatment week. These measures of inhibitory control can be assessed during NoGo trials on the Go/NoGo task. Mean number of pumps on the BART task will represent risk-taking. Positive and negative feedback during the BART task can be used to study electrophysiological responses (See paragraph 8.3 page 17 of protocol). Number of cigarettes (and craving) per day starting on the first tDCS day until one week after the last tDCS intervention (total of 14 days) to study the course of cigarette consumption during and after tDCS.

—

Secondary

Measure	Time frame
Levels of carbon monoxide on the days that subjects are visiting the Erasmus Behaviors Lab, to control for EMA logged number of cigarettes. Furthermore, the following control variables will be assessed: positive- and negative affect, alcohol/ drug use, life satisfaction, amount of drug use in the past month, starting age of using drugs and current age.	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)