Appendicitis inflammation of the appendix
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Children between 5 and 18 years old, who are referred by first line health care with the suspicion of acute appendicitis. Healthy children between 5 and 18 years old
Exclusion criteria
Exclusion criteria: Severe co-morbidity like malignancy, resent abdominal surgery and known inflammatory bowl disease. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are the bacteria and viruses present, and their mutual frequence ratio, in the wall of the resected inflamed appendix together with the presence of these bacteria and gastrointestinal viruses in feces and the viruses in the blood samples. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other parameters that will be analyzed are patient factors like diagnosis (perforated or non-perforated appendicitis), age and gender. Furthermore, information on possible confounding factors, such as use of antibiotics or other medicine, use of probiotics, and diet, will be collected. | — |
Countries
Netherlands
Outcome results
None listed