Complex Regionaal Pijn Syndroom nerve pain post traumatic dystrophy
Conditions
Interventions
Oxygen is applied as an intervention to examine and compare its effect on the
oxygenation in healthy participants and CRPS patients.
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria CRPS-I patients: CRPS-I according to 2012 IASP (Budapest) criteria: Harden RN, Bruehl S, Perez RS, et al. Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain Syndrome. Pain 2010; 150: 268-274.;Inclusion criteria pain controls: Patients diagnosed with Radiculopathy with pain in one extremity as main symptom;Inclusion criteria healthy controls: >18 years old, healthy (no neurological, cardiac, pulmonary, renal or vascular diseases diagnosed)
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study:;- Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tissue oxygenation in both static and dynamic conditions will be compared between CRPS-affected and unaffected limbs and between CRPS patients, pain controls and healthy controls. Furthermore, differences in tissue oxygenation in static and dynamic measurements and correlations with pain, skin temperature variations, and disease duration will be determined. | — |
Secondary
| Measure | Time frame |
|---|---|
| The correlation between oxygenation and skin temperature with experienced pain, amount of limb movement, and disease duration will be investigated as well. | — |
Countries
Netherlands
Outcome results
None listed