blood pressure Pharmacokinetics
Conditions
Interventions
Participants will receive 1-wk of dietary guidance in which they will be
provided with a sufficient amount of vegetables, representing 400 mg (6.5 mmol)
nitrate per serving (i.e. each day), includin
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Healthy (not being diagnosed with a cardiovascular or metabolic disease and/or no presence of mental/psychological conditions) - 18 - 45 years of age - 18.5 2 h/week) ;(page 18, protocol)
Exclusion criteria
Exclusion criteria: - Use of medication - Smoking - Currently supplementing diet with nitrate;(page 18, protocol)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary parameter will be the increase in plasma nitrate concentrations from baseline fasting levels (which will be measured at 3h post-ingestion on day 1, 4, and 7 of the intervention) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters: - plasma nitrite concentrations - salivary nitrate and nitrite concentrations - blood pressure - urinary nitrosamines - dietary intake | — |
Countries
Netherlands
Outcome results
None listed