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Measuring the Activated Clotting Time in patients receiving unfractionated heparin prior to coronary angiography and intervention. A single-centre validation study comparing different blood sampling sites

Measuring the Activated Clotting Time in patients receiving unfractionated heparin prior to coronary angiography and intervention. A single-centre validation study comparing different blood sampling sites - Validation of ACT measurements

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON43038
Enrollment
100
Registered
2017-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

coronary angiography
heparin

Sponsors

Medisch Centrum Alkmaar
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Consecutive patients scheduled for diagnostic coronary angiography or elective percutaneous coronary intervention (PCI) are screened for entry into this study. Patient are eligible for this study when it is expected that the scheduled procedure will be accomplished with a single bolus of heparin, i.e. patient undergoing a procedure with expected duration of > 1 hour will not be included in this study.

Exclusion criteria

Exclusion criteria: - Use of novel oral anticoagulants or vitamin K antagonists - Chronic use of non-steroid anti-inflammatory drugs with the exception of aspirin - Known renal insufficiency (e.g. serum creatinine level of more than 265 *mol/L (i.e. more than 3.5 mg/L)) - Liver function disorders with coagulopathies (PT >1.5N, INR >2.0 and/or thrombocyte count

Design outcomes

Primary

MeasureTime frame
Variability in ACT measurements at different blood sampling sites at the end of coronary angiography or intervention in patients receiving pre-procedural UFH.

Secondary

MeasureTime frame
N.A.

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)