Het onderzoek wordt bij gezonde proefpersonen uitgevoerd. Uitkomsten uit deze lijn van onderzoek bieden nieuwe handvatten voor verklaringsmodellen en therapeutische interventies voor aandoeningen waarbij jeuk een symptoom is. Not applicable
Conditions
Sponsors
Universiteit Leiden
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Between 18 and 35 years old; good understanding of written and spoken Dutch
Exclusion criteria
Exclusion criteria: Refusal to give written informed consent; severe somatic or psychological morbidity (e.g., heart and lung diseases or DSM-IV psychiatric disorders) that would adversely affect participant's safety or that might interfere with the study protocol; current chronic itch or pain complaints; current use of analgesics, anti-inflammatory drugs, antihistamines, antibiotics or recent vaccinations; pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameter is self-reported itch during histamine iontophoresis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study outcomes include wheal size, flare response, skin temperature, and self-reported skin condition following histamine iontophoresis, as well as scratching behaviour. In addition, the possible influence of psychological parameters on outcomes will be explored. | — |
Countries
Netherlands
Outcome results
None listed