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Repeat CT for evaluation of inter- and intrafraction changes during curative thoracic radiotherapy; An exploratory pilot study.

Repeat CT for evaluation of inter- and intrafraction changes during curative thoracic radiotherapy; An exploratory pilot study. - REACT-study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON43004
Enrollment
80
Registered
2016-09-23
Start date
2016-12-08
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(non) small cell lung cancer stage 3 breast cancer or (non) Hodgkin lymphoma Patients with esophageal cancer

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Histologically proven esophageal cancer, stage III NSCLC or SCLC, breast cancer, or (non) Hodgkin lymphoma. - Scheduled for external-beam photon radiotherapy to the thoracic region with curative intention. - Scheduled for (neo-)adjuvant or primary (chemo)radiotherapy. - WHO 0-2. - Age >= 18 years. - Written informed consent.

Exclusion criteria

Exclusion criteria: - Relative contra-indications, such as pain, for lying on the treatment or CT couch. - Non compliance with any of the inclusion criteria.

Design outcomes

Primary

MeasureTime frame
Dose coverage of the target volumes (CTVs).

Secondary

MeasureTime frame
• Margin for inter-fraction variation (in relation to the ITV and PTV margin) • Areas of under dosage • Areas of over dosage • DVH parameters of the heart (MHD, V5, V10, V20, V30, V40, V50, V60) • DVH parameters of the lungs (MLD, V5, V10, V20, V30, V40, V50, V60)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)