voeding supplementen glutamine
Conditions
Interventions
After informed consent is obtained patients are randomised to receive enteral
glutamine or not ( the control group). Enteral glutamine supplementation is
started (day 1) at a dose of 3 sachets per d
Sponsors
Medisch Centrum Leeuwarden
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All patients admitted to the ICU with an expected stay of 48 hours or longer
Exclusion criteria
Exclusion criteria: age under 18 years, readmission to the ICU, contra-indication for enteral nutrition and the use of Total Parental Nutrition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Is there a difference in length of mechanical ventilation, length of stay ICU or length of stay hospital between patients who received enteral glutamine or not? | — |
Secondary
| Measure | Time frame |
|---|---|
| What is the amount of enteral glutamine supplementation needed to increase the plasma glutamine level to a level above 420 µmol/l.Is there a difference between hospital mortality or 6 month mortality between patients who received enteral glutamine or not? Is there a relationship between nutritional status ( measured with bio-impedance vector analysis) and plasma glutamine level? Is there a relationship between the amount of supplied nutrition and the course of plasma glutamine levels? Is there a difference between patients admitted with sepsis or trauma compared to other causes of admission? | — |
Countries
Netherlands
Outcome results
None listed