Photoreceptor damage in uveitis measured by ElectroRetinoGram

Photoreceptor damage in uveitis measured by ElectroRetinoGram - ERG Uveitis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42971

Enrollment

200

Registered

2016-05-24

Start date

2016-08-02

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anterior and/or intermediate and/or posterior uveitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age *18 years Diagnosed with uveitis Mentally competent

Exclusion criteria

Exclusion criteria: Patients who do not speak or understand the Dutch language will be excluded from participation in this study. Age *18 years Patients with a family history of retinal dystrophy.

Design outcomes

Primary

Measure	Time frame
The retinal function measured by ERG is the main outcome of the study. ERG reduction, reflecting retinal damage, will be analysed throughout the course of uveitis. ERGs will be evaluated on several parameters, including a and b wave amplitude, latency, waveform, b:a wave ratio, and oscillatory potentials.	—

Secondary

Measure	Time frame
- When ERG reduction, reflecting retinal damage, occurs in the course of uveitis. - To which extent different forms of uveitis, i.e. anterior, intermediate, posterior, panuveitis or specific diagnosis influence ERG abnormalities - To which extent clinical parameters, including demographics, treatment and ophthalmologic examination results (e.g. visual acuity, severity of inflammation scored according to the SUN criteria18, flare, presence of CME, retinal vasculitis or chorioiditis on FA, OCT values and visual fields) influence ERG abnormalities. - To which extent ERG abnormalities are reversible.	—

Measure

Time frame

- When ERG reduction, reflecting retinal damage, occurs in the course of uveitis. - To which extent different forms of uveitis, i.e. anterior, intermediate, posterior, panuveitis or specific diagnosis influence ERG abnormalities - To which extent clinical parameters, including demographics, treatment and ophthalmologic examination results (e.g. visual acuity, severity of inflammation scored according to the SUN criteria18, flare, presence of CME, retinal vasculitis or chorioiditis on FA, OCT values and visual fields) influence ERG abnormalities. - To which extent ERG abnormalities are reversible.

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Countries

Netherlands

Outcome results