mild cognitive impairment mild memory problems
Conditions
Interventions
Healthy older adults will visit the hemodynamics laboratory three times. During
one visit participants will have to perform sit-to-stand alternations for four
times five minutes in total, with inter
Sponsors
Geriatrie
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Males and females aged >=60 Living independently at home Physical ability sufficient to allow performance of exercise Normal or corrected-to-normal vision Stable medical condition for more than 6 months Stable medications for more than 2 months
Exclusion criteria
Exclusion criteria: Experience of subjective memory problems History of serious neurological disorder History of any major psychiatric disorder Significant history of alcoholism or drug abuse within the last 10 years History of myocardial infarction within previous year Unstable cardiac, renal, lung, liver, or other chronic disease Uncontrolled hypertension or hypotension Congestive heart failure (NYHA class II, III or IV) Diabetes Use of psychopharmacological drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in functional prefrontal activation as determined by oxygenated hemoglobin changes (µmol/L) induced by cerebral blood flow perturbations. | — |
Secondary
| Measure | Time frame |
|---|---|
| - | — |
Countries
Netherlands
Outcome results
None listed