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Anabolic properties of BCKA and BCAA in vivo in older men

Anabolic properties of BCKA and BCAA in vivo in older men - Keto study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON42909
Enrollment
55
Registered
2016-10-06
Start date
2017-01-17
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Het onderzoek zal worden uitgevoerd in gezonde proefpersonen loss of skeletal muscle mass Sarcopenia

Interventions

Muscle
Protein
A beverage (300 mL) containing 6 g of BCAA, 6 g of BCKA- or 30 g of milk protein will be consumed (n=15 per group).
Keto acids

Sponsors

Evonik Industries
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Healthy males Age between 65 and 80 y BMI between 18.5 and 30 kg/m2

Exclusion criteria

Exclusion criteria: Lactose intolerance Smoking Diabetes Diagnosed GI tract diseases Arthritic conditions A history of neuromuscular problems Any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). Use of anticoagulants Participation in exercise program Hypertension, high blood pressure that is above 140/90 mmHg Females (in order to have a more homogenous group)

Design outcomes

Primary

MeasureTime frame
Primary study parameters include post-prandial plasma amino acid availability and myofibrillar muscle protein synthesis rates.

Secondary

MeasureTime frame
Secondary study parameters include whole-body protein synthesis, breakdown, oxidation, and net balance.

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)