Het onderzoek zal worden uitgevoerd in gezonde proefpersonen loss of skeletal muscle mass Sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy males Age between 65 and 80 y BMI between 18.5 and 30 kg/m2
Exclusion criteria
Exclusion criteria: Lactose intolerance Smoking Diabetes Diagnosed GI tract diseases Arthritic conditions A history of neuromuscular problems Any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). Use of anticoagulants Participation in exercise program Hypertension, high blood pressure that is above 140/90 mmHg Females (in order to have a more homogenous group)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary study parameters include post-prandial plasma amino acid availability and myofibrillar muscle protein synthesis rates. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters include whole-body protein synthesis, breakdown, oxidation, and net balance. | — |
Countries
The Netherlands