Cognitieve beperkingen cognition overweigt
Conditions
Interventions
Participants will receive a daily dose of BrainPort (high or low dose) or
placebo for a period of 6 months. The capsules of BrainPort or placebo have to
be ingested every day 30 minutes before the f
cognition
Polyphenols
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Healthy individuals, age: 40-60 years, BMI 25-35 kg/m2
Exclusion criteria
Exclusion criteria: - History of severe cardiovascular, respiratory, urogenital, gastrointestinal/hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat). Dermatological/connective tissue, musculoskeletal, metabolic/nutritional, endocrine, neurological diseases, allergy, major surgery and /or laboratory assessments that might limit participation in or completion of the study protocol. - Diabetes - Use of medication that might have influence on endpoints (e.g. hypertension medication) - Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study in the 180 days prior to the study - Use of antibiotics in the 30 days prior to the start of the study - Use of antioxidants, minerals and vitamin supplements available in pharmacies, drugstores, food markets or in alternative medicine - Pregnancy, lactation - Abuse of products (> 20 alcoholic consumptions per week and drugs) - Smoking - Weight gain or loss (> 3 kg in previous 3 months) - High physical activity (>4.5 hours of running/week) - History of any side effects towards intake of berries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary efficady parameter is cognition, as assesed by a cognitive test battery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objectives include the assessment of BrainPort on intima-media thickness of the carotis, flavo-enzymes, liver function, and blood pressure. | — |
Countries
The Netherlands
Outcome results
None listed