Reproducibility and correlation with clinical severity of the McManis long-exercise test in patients with hypokalemic periodic paralysis

Reproducibility and correlation with clinical severity of the McManis long-exercise test in patients with hypokalemic periodic paralysis - LET in HypoPP study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42874

Enrollment

Registered

2016-04-29

Start date

2016-05-16

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypokalemic periodic paralysis (HypoPP)

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. At least 16 years of age 2. Genetically confirmed diagnosis of HypoPP

Exclusion criteria

Exclusion criteria: 1. Inability or unwillingness to provide informed consent 2.Other neurological conditions that might affect the assessment of the study measurements 3. Any reason why the tests cannot be performed on both hands

Design outcomes

Primary

Measure	Time frame
- The intraclass correlation coefficient (ICC) of the maximum percentage decrease of the compound muscle action potential (CMAP) of all ten patients on all four measurements - The correlation coefficient between the clinical severity and the mean maximum decrease of the CMAP measured over the four LET's.	—

Countries

Netherlands

Outcome results