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The influence of Annexin A2 SNP (rs17845226) on von Willebrand factor secretion by endothelial cells

The influence of Annexin A2 SNP (rs17845226) on von Willebrand factor secretion by endothelial cells - VWF secretion Annexin A2 (rs17845226)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON42870
Enrollment
Unknown
Registered
2016-05-25
Start date
2016-10-10
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

von Willebrand disease VWD

Interventions

None listed

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Participant of the Nijmegen Biomedical Study (NBS) with informed consent to be contacted for further research. - Homozygous or heterozygous for the Annexin A2 SNP rs17845226 (c.346G>T), or WT.

Exclusion criteria

Exclusion criteria: - No written informed consent for study participation obtained from the subject.

Design outcomes

Primary

MeasureTime frame
This study is a laboratory driven study. The main study endpoint is the elucidation of the Annexin A2 dependent VWF secretion pathway.—

Secondary

MeasureTime frame
N.A.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)