transcraniale prefrontale stimulatie met gezonde proefpersonen This study is not aimed at a certain disorder. It is a study with healthy subjects.
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: [1] Healthy males and females, [2] 18 years old or older, [3] Normal (or corrected to normal) vision, [4] Right-handed
Exclusion criteria
Exclusion criteria: [1] (History of) significant medical, psychiatric or neurological conditions, [2] Metal implants in the body (e.g., pacemaker, heart valves, vascular clips, eye-implants, copper containing intra-uterine devices, non-removable piercing, cerebral implants), [3] Any risk of having metal particles in the eyes, [4] Tattoos containing iron oxide, [5] (Suspected) pregnancy, or breast feeding [6] Claustrophobia, [7] Drug or alcohol abuse, [8] Use of psycho-active medication, [9] Refusal to be informed about structural brain abnormalities, [10] Epilepsy or family history of epilepsy, [11] Use of medication associated with increased epileptic seizure risk, [12] Neurological problems in the past or present (including brain surgery, infarction, stroke, and the intake of medication that could increase the risk of stroke), [13] Severe scalp skin lesions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are the changes in blood-oxygenation-level dependent (BOLD) signal induced by transcranial brain stimulation. We will measure the BOLD signal at rest and during the performance on two different tasks tapping executive functions using fMRI. | — |
Secondary
| Measure | Time frame |
|---|---|
| In addition, we will measure cerebral blood flow (CBF) using the arterial spin labeling technique, and we will record MR spectroscopy data from the dorsal striatum. | — |
Countries
Netherlands
Outcome results
None listed