geen aandoeningen: gezonde vrijwilligers, pijn en pijnverwerking Pain and painmodulation
Conditions
Interventions
Music
Pain
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 18 years or older and they have knowledge of the Dutch language.
Exclusion criteria
Exclusion criteria: the use of painkillers in the last 12 hours, use of anti-depressants, pain in arm neck or shoulder (one or both sides), heart problems, neurological disorders, psychiatric disorders, wounds on hands or forearm, M. Raynaud, pregnancy, alcohol percentage of > 220 UGL.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters/endpoints: Pressure tolerance will be measured via algometry (Wagner force, USA) on five places on the dorsal side of the non dominant forearm and expressed in Newton (N). Electrical pain tolerance thresholds are assessed on two places on the dorsal side of the nondominant forearm and expressed in milliAmpere (mA). Duration in the icewaterbucket (IWB) with the dominant hand will be recorded in seconds (s) with a maximum of three minutes (180s). After the IWB test the pressure tolerance or the electrical pain tolerance thresholds will be recorded again. Conditioned pain modulation (CPM) will be calculated by use of the formula ((pressure post-pressure pre)/pressure pre)*100 expressing the precentage of painmodulation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are the sensitivity for pain (assessed with the Pain Sensitivity Questionnaire (PSQ), amount and quality of sleep (Pittsburg Sleep Quality Index) and the Quality of Life (assessed with the EQ-5D).In addition, the subject will be asked after the completion of the investigation how burdensome they found the measurements. | — |
Countries
The Netherlands
Outcome results
None listed