Toxiciteit in speekselklieren van uitwendige bestraling Salivary gland toxicity Xerostomia
Conditions
Interventions
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Patients with HNSCC, who were treated 6-12 months ago with (CC)RT of one neck side with curative intent, and who received variable doses to the major salivary glands at the irradiated side with at least one gland receiving a significant part >36Gy EQD2.
Exclusion criteria
Exclusion criteria: Pregnancy, lactation, inability to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The image quality will be evaluated visually with respect to spatial resolution, signal-to-noise levels and artefacts. The signal reduction due to external beam irradiation will be interpreted visually, while considering relatively spared regions and known normal uptake patterns in healthy gland tissues. An expert panel will review if the PSMA PET/CT scans are adequate (feasible) for the application in the anticipated study protocol. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
The Netherlands
Outcome results
None listed