Trans-abdominal ultrasound as a point-of-care test for the assessment of disease activity in patients with ulcerative colitis

Trans-abdominal ultrasound as a point-of-care test for the assessment of disease activity in patients with ulcerative colitis - UltraSound for ULceraticve colitis (USeFUL)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42820

Enrollment

Registered

2015-12-22

Start date

2016-05-10

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inflammatory bowel disease ulcerative colitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Histo-pathologically confirmed diagnosis of UC - Quiescent disease, mild to moderate active disease or moderate to severe active disease according to the Montreal classification - Needing a endoscopy with biopsies for evaluation of the disease

Exclusion criteria

Exclusion criteria: - Pregnancy - Age 30 kg/m²) - Coagulation disorders - Use of warfarins

Design outcomes

Secondary

Measure	Time frame
other parameters: endoscopic disease activity (UCEIS, Mayo), clinical disease activity (SCCAI, Mayo), biochemical disease activity (inflammatory parameters), patient satisfaction, examination costs.	—

Primary

Measure	Time frame
Candidate parameters for the ultrasound index: colon wall thickness, colon wall layer stratification, mucosa thickness, submucosa thickness, muscularis propria thickness, colon wall perfusion, superior mesenteric artery (SMA) blood flow, inferior mesenteric artery (IMA) blood flow, colon visibility, colon contents, disease extent (affected area), haustra coli visibility, mesenteric lymphnodes,	—

Countries

Netherlands

Outcome results