The aetiology of nocturnal symptoms in carpal tunnel syndrome

The aetiology of nocturnal symptoms in carpal tunnel syndrome - Nocturnal symptoms in carpal tunnel syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42718

Enrollment

Registered

2015-09-01

Start date

2015-09-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

carpal tunnel syndrome compression neuropathy of the median nerve nerve entrapment in the wrist

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Electrophysiologically proven CTS • History of nocturnal complaints of CTS leading to awakening >= two times per night • Age >= 18 years • Ability to provide informed consent

Exclusion criteria

Exclusion criteria: • Working night shifts during the study period • Any skin condition of the hand that would make wearing of the Leiden Wrist Goniometer (LWG) uncomfortable. • The need for immediate surgery or other treatment for CTS • Any reason patients can not wear an ABPM on the contralateral arm, such as previous brachial lymphadenectomy

Design outcomes

Primary

Measure	Time frame
Hypothesis 1: There is a specific position of the wrist causing nocturnal symptoms. 1a.) This position is the same in all patients. Parameter: The average angle of the wrist 15 minutes before every awakening compared to the average angle of the wrist during 15 minutes at the same time in another night in which the patient did not awake at that time. Hypothesis 2: Nocturnal symptoms of CTS are related to a prolonged position of the wrist. Parameter: variance in position of the wrist during the 60 minutes prior to awakening compared with to variance in position during the same 60 minutes in another night in which the patient did not awake at that time.	—

Measure

Time frame

Hypothesis 1: There is a specific position of the wrist causing nocturnal symptoms. 1a.) This position is the same in all patients. Parameter: The average angle of the wrist 15 minutes before every awakening compared to the average angle of the wrist during 15 minutes at the same time in another night in which the patient did not awake at that time. Hypothesis 2: Nocturnal symptoms of CTS are related to a prolonged position of the wrist. Parameter: variance in position of the wrist during the 60 minutes prior to awakening compared with to variance in position during the same 60 minutes in another night in which the patient did not awake at that time.

—

Secondary

Measure	Time frame
Hypothesis 3: Nocturnal symptoms of CTS are related to nocturnal drop in systemic BP. Parameter: BP preceding nocturnal symptoms compared to BP on a random chosen moment in that night in which the patient did not awake. Hypothesis 4: Splinting of the wrist in neutral position results in a decrease of the frequency of nocturnal symptoms of CTS of at least 50%. Parameter: average frequency of awakenings during the first week compared to the second week.	—

Measure

Time frame

Hypothesis 3: Nocturnal symptoms of CTS are related to nocturnal drop in systemic BP. Parameter: BP preceding nocturnal symptoms compared to BP on a random chosen moment in that night in which the patient did not awake. Hypothesis 4: Splinting of the wrist in neutral position results in a decrease of the frequency of nocturnal symptoms of CTS of at least 50%. Parameter: average frequency of awakenings during the first week compared to the second week.

—

Countries

Netherlands

Outcome results