The onset of walking and freezing in Parkinson patients compared to controls: A combined EEG-EMG study

The onset of walking and freezing in Parkinson patients compared to controls: A combined EEG-EMG study - Walking and freezing in PD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42689

Enrollment

Registered

2015-12-15

Start date

2016-02-11

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy individuals: o Perceived healthy o Age >= 18 years, age- and sex-matched with PD patients without FOG for case-control study o Right-handed according to the Annett Handedness scale o Written informed consent All PD Patients: o able to walk properly (Hoehn & Yahr scale: Stage 2-3) o PD diagnosis according to the UK Parkinson*s Disease Society Brain Bank criteria (A.J. Hughes, 1992) o Age =1 on (Dutch translation of) Giladi*s FOG questionnaire (Giladi et al., 2000) or presence of FOG on clinical examination during rapid bidirectional 360 degree turns and dual tasking (Snijders et al., 2012)

Exclusion criteria

Exclusion criteria: All participants • Mini Mental State Examination (MMSE) score

Design outcomes

Primary

Measure	Time frame
Measures of cortico-cortical, cortico-muscular and musculo-muscular coupling (derived from dynamic coherence analysis) during the different tasks, compared between patients with and without FOG and controls. In addition, measures of gait such as step duration, gait velocity and walking rhythm during the different tasks, compared between patients and controls.	—

Countries

Netherlands

Outcome results