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The feasibility of preparing untreated esophageal adenocarcinoma endoscopic biopsies towards DNA/RNA samples suitable for next-generation sequencing.

The feasibility of preparing untreated esophageal adenocarcinoma endoscopic biopsies towards DNA/RNA samples suitable for next-generation sequencing. - DNA/RNA from esophagealcarcinoma biopsies suitable for sequencing.

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON42638
Enrollment
20
Registered
2015-10-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer esophageal carcinoma

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Studypopulation: patients who are diagnosed with esophageal adenocarcinoma and who undergo endoscopic ultrasonography. Inclusion criteria: written informed consent, patients fit for CROSS therapy and surgical resection.

Exclusion criteria

Exclusion criteria: Exclusion criteria: incompetent,

Design outcomes

Primary

MeasureTime frame
The number of DNA and RNA samples suitable for next-generation sequencing. To assess this number, the following criteria have to be determined: - The amount of tumorsamples directly frozen after biopsy - The percentage of tumorcells in the biopsies - The amount of DNA in the biopsies - The amount of RNA in the biopsies—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)