obsessive-compulsive disorder OCD in psychosis
Conditions
Interventions
Manualized CBT will be applied over a period of 12 weeks.
Sponsors
Psychiatrie
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Obsessive-compulsive symptoms (YBOCS * 12 for at least 2 months) 2) Age range of 18 to 50 years 3) Diagnosis of a schizophrenia spectrum disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5 5) Good command of the Dutch language 6) Able and willing to give written informed consent
Exclusion criteria
Exclusion criteria: 1) Rumination or repetitive behaviour solely related to psychotic symptoms. Positive symptoms as such are not an exclusion criterion; only when they are considered to be the primary cause of OCS-like symptoms or when they are so severe that primary treatment focused on positive symptoms is called for (more than one PANSS item of the positive subscale has a score of 5 or when one PANSS item of the positive subscale has a score of 6 or more). 2) Sever intellectual impairment, defined as an estimated IQ
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the change in OCS severity as assessed by the Yale-Brown-Obsessive-Compulsive Scale (YBOCS) compared to the waiting list condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are changes in symptoms of psychosis and depression, social functioning, and quality of life. | — |
Countries
Netherlands
Outcome results
None listed