Depression mood
Conditions
Interventions
* Multi-nutrient supplement: comprising 2 pills a) Omega 3 fatty acids: 1000 mg
per capsule with a EPA/DHA ratio 3:1 (EPA > 700 mg per capsule, DHA > 100 mg
per capsule) b) Multivitamin/minerals pil
6 group-based sessions -1h-) with a
trained therapist who will target the determines and idiosyncratic triggers of
unhelpful (e.g., mood related snacking) and helpful food related behavior.
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age 18*75 years, 2) BMI *25 - 40 kg/m2, 3) High depressive symptom score (PHQ-9 score > 5)
Exclusion criteria
Exclusion criteria: 1) Current clinical depression diagnosis (according to psychiatric DSM*IV criteria as determined with the MINI international neuropsychiatric interview); 2) Current use of antidepressant drugs or psychological interventions, 3) History of psychosis, bipolar disorder, substance, dependence or other severe, psychiatric disorder that requires specialized clinical attention, 4) History of bariatric surgery or current severe, life*threatening disease.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| * Depressive Symptomatology assessed with the Patient Health Questionnaire (PHQ-9, Kroenke et al, 2001) * Food intake (FFQ-GA2LEN) * Food behaviour and sustainability: * Food and eating behaviour: The Three-factor Eating Questionnaire (TFEQ-21; Cappelleri et al, 2009) * Physical activity and sedentary behaviour with validated questionnaires (Short Questionnaire to Assess Health - Enhancing Physical Activity (SQUASH, Wendel-Vos 2003) and sedentary behaviour (SBQ67) * Body weight perception: The Stunkard figure rating scale (Stunkard et al.,1983) * Generalized Anxiety Disorder Assessment (GAD-7; Spitzer et al, 2006) for anxiety symptoms * Quality of life (EuroQol instrument, EQ-5D-5L, EuroQol group, 1990) * Automaticity of good and bad health behaviours and compliance to Mediterranean diet (Self-reported behavioural automaticity index (SRBAI) * Behavioural functionality: activation, avoidance/rumination, work /school impairment and social impairment (The behavioural activation for depression scale (BADS) | — |
Primary
| Measure | Time frame |
|---|---|
| * The 12 month cumulative incidence of Major Depressive Disorder (MDD), defined according to the standard psychiatric DSM-IV criteria using MINI (Mini International Neuropsychiatric Interview): baseline, 6 and 12 months later1. * Depressive symptomatology according the Inventory of Depressive Symptomatology2;3 baseline, 3, 6, 12 months later. | — |
Countries
Netherlands
Outcome results
None listed