Minimally invasive determination of oxygen extraction ratio in patients undergoing cardiac surgery

Minimally invasive determination of oxygen extraction ratio in patients undergoing cardiac surgery - VooDoo study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42604

Enrollment

Registered

2015-07-17

Start date

2015-09-29

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac surgery open heart surgery

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Elective cardiac surgery * Older than 18 years * Presence of a pulmonary artery catheter and central venous line

Exclusion criteria

Exclusion criteria: * Re-operation * Aortic valve surgery in cas of severe aortic stenosis * Bentall surgery * Arrhythmias (may dampen the signal of pulse oximetry) * Anemia (Hemoglobin levels of 5.5 mmol/L or lower; decreases oxygen delivery) * Severe COPD (adaptation of peripheral microvasculature to chronic hypoxia; Gold 3/4) * Intra-cardiac shunt * ASA score of 4 and higher and NYHA score exceeding 4

Design outcomes

Primary

Measure	Time frame
Invasive and minimal invasive measurements of DO2, VO2 and the oxygen extraction ratio.	—

Secondary

Measure	Time frame
* Cardiac output * Hemoglobin measurements in the laboratory and using a point of care device * SpO2 * SaO2 * SvO2/ScvO2 * O2ER * Lactate	—

Countries

Netherlands

Outcome results