Daytime pupil response and alertness photoreceptor adaptation pupil response
Conditions
Interventions
Licht met een fluctuatie in intensiteit met een frequentie van 0, 0.5, 1, 2, 4
en 8 Hz.
Sponsors
Rijksuniversiteit Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: healthy men and women (18-30 y) normal chronotype normal sleep duration women using a hormonal form of birth control (steady hormone levels)
Exclusion criteria
Exclusion criteria: short (9h) going out more than two nights a week until minimally 7AM extreme early or late chronotype chronic (psychiatric or somatic) disease sleep disorder eye complaints or eye surgery in the past (excluding use of contact lenses) use of chronic (photosensitizing) medication in 3 months prior to start of stydt regulary use of sleep medication or stimulating drugs colour blindness more than 3 glasses of alcohol on working days, and or the regularly use of drugs more than 8 caffeinated drinks per day regularly napping (more than 2 times a week) shiftwork in 3 months prior to the start of the study travelled across more than 1 timezone in the month prior to the start of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pupillary unrest index, pupil response (constriction and adaptation during exposure to light) | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed