The Anterior Cutaneous Nerve Entrapment Syndrome (ACNES). Retrograde transforaminal paresthesia mapping (RTPM) for patients with ACNES. A pilot study for the anatomical distribution of neuropathic pain in the trunk at the level of the dorsal root ganglion.

The Anterior Cutaneous Nerve Entrapment Syndrome (ACNES). Retrograde transforaminal paresthesia mapping (RTPM) for patients with ACNES. A pilot study for the anatomical distribution of neuropathic pain in the trunk at the level of the dorsal root ganglion. - ACNES-RETROMAP

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42590

Enrollment

Registered

2015-07-01

Start date

2015-08-13

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

entrapped nerve abdominal wall intercostal neuralgia

Interventions

Retrograde transforaminal paresthesia mapping (RTPM) followed by pulsed radio frequency (pRF) treatment.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: •Clinical diagnosis of ACNES: •Localisation ACNES unilateral •Clear, discrete pain point over the m. rectus abdominis •Symptoms get worse upon flexing the abdominal muscles (Carnett*s sign positive) •Good temporary effect of one local injection at the ACNES pain point with a local anesthetic. ;•Informed consent obtained and good apprehension of the procedure warranted •Minimum age 18 years

Exclusion criteria

Exclusion criteria: •Pregnancy •Allergy or hypersensitivity to lidocaine •Prior treatment for ACNES, such as peripheral nerve blocks, Pulsed-Radio-Frequency, epidural injections, etc. •Adequate follow-up not warranted, for example because of mental retardation, dementia or a language barrier •Spinal surgical procedures at or between vertebral levels Th8-L2 in medical history •Known coagulation disorders or use of anticoagulants

Design outcomes

Primary

Measure	Time frame
The number of patients who confirm a one to one correlation between the clinical suspected anatomical dermatome in which their ACNES pain point is located and the corresponding dorsal root ganglion with RTPM	—

Secondary

Measure	Time frame
Electrophysiological aspects: - If no one to one correlation is present, what is the mean number of DRGs involved. - The relative contribution per DRG of elicited pain in the pain point in percentages. - Anatomical distribution of the elicited paresthesia using a drawing map - The mean mV to illicit a pain response. Differentiation between peripheral and central sensitized pain: - The number of patients who report instantaneous complete remission of pain caused by a procedure after local anaesthesia in the targeted DRGs. Pain reduction: - Mean pain reduction on a Numeric Pain Rating Scale after PRF treatment compared to baseline directly after treatment and 2 weeks and 6 weeks after treatment. - The percentage of patients with a >30% and >50% pain reduction on a NPRS.	—

Measure

Time frame

Electrophysiological aspects: - If no one to one correlation is present, what is the mean number of DRG*s involved. - The relative contribution per DRG of elicited pain in the pain point in percentages. - Anatomical distribution of the elicited paresthesia using a drawing map - The mean mV to illicit a pain response. Differentiation between peripheral and central sensitized pain: - The number of patients who report instantaneous complete remission of pain caused by a procedure after local anaesthesia in the targeted DRG*s. Pain reduction: - Mean pain reduction on a Numeric Pain Rating Scale after PRF treatment compared to baseline directly after treatment and 2 weeks and 6 weeks after treatment. - The percentage of patients with a >30% and >50% pain reduction on a NPRS.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)