Hereditary Thrombophilia in the Pathogenesis of Myocardial Infarction and Coronary Artery Bypass Graft Occlusion: New Role for an Old Actress.

Hereditary Thrombophilia in the Pathogenesis of Myocardial Infarction and Coronary Artery Bypass Graft Occlusion: New Role for an Old Actress. - HERITAGE-ACS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42575

Enrollment

887

Registered

2016-01-26

Start date

2016-03-14

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute coronary syndrome Heart attack

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with unstable angina or non-ST-segment elevation myocardial infarction. Age above 18 years;ST-segment elevation myocardial infarction (STEMI) patients for comparison will be selected from an existing dataset of ongoing trial (i.e., POPular Genetics).

Exclusion criteria

Exclusion criteria: Patients who are unable or unwilling to give informed consent (e.g., due to metal illnesses or inability to understand Dutch language). Individuals younger than 18 years of age. Patients with previous ST-segment elevation myocardial infarction (STEMI)

Design outcomes

Primary

Measure	Time frame
Prevalence of factor V Leiden or Prothrombin G20210A in STEMI as compared to NSTEMI/uAP patients.	—

Secondary

Measure	Time frame
Hemorrhagic complications during the index hospitalization in patients with versus without factor V Leiden or prothrombin G20210A mutations.	—

Countries

Netherlands

Outcome results