Biomarkers for disease activity of juvenile idiopathic arthritis

Biomarkers for disease activity of juvenile idiopathic arthritis - Biomarkers in JIA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42570

Enrollment

200

Registered

2015-04-30

Start date

2015-05-18

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childhood Arthritis Juvenile Idiopathic Arthritis

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Clinically suspected JIA or diagnosed with JIA. Scheduled to undergo MRI of the affected joint. Written informed patients (when >12 years of age) and parental consent OR JIA patients with clinically inactive disease for at least 6 months. A history of clinical evident arthritis in at least 1 joint. Scheduled to undergo MRI of knee, hand/wrist, ankle or SI joint. Written informed patients (when >12 years of age) and parental consent.

Exclusion criteria

Exclusion criteria: Age 18 years. General contraindications for MRI (such as renal insufficiency, pregnancy and claustrophobia) Lack of written informed consent

Design outcomes

Primary

Measure	Time frame
The accuracy, validity, correlation, predictive value and responsiveness to change of physical examination, imaging and biomarkers for the clinical course in JIA patients.	—

Secondary

Measure	Time frame
The construction of a prediction model in JIA disease activity The evaluation of high resolution, 3.0T MRI characteristics in the different JIA subtypes	—

Countries

Netherlands

Outcome results