Heart rate variability measurement to assess disease activity in patients with Crohn's disease, a cross-sectional study

Heart rate variability measurement to assess disease activity in patients with Crohn's disease, a cross-sectional study - Heart rate variabilitity (HRV) in Crohn's disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42566

Enrollment

Registered

2015-10-26

Start date

2015-11-09

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease inflammatory bowel disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients 18-80 years old, either female or male Active CD/inactive CD Indication for endoscopy (disease evaluation) BMI range between 17.5 and 30 kg/m2

Exclusion criteria

Exclusion criteria: Comorbidity - Cardiac arrhythmias, Hyper-, Hypotension, Peripheral vascular disease, Diabetic mellitus - Splenectomy - Infectious diseases: acute or chronic infections - Depression - Kidney failure - Pulmonary diseases: upper- and lower respiratory diseases, Asthma Medication - Short- and Long acting Beta-agonist - Beta 1 and 2 -blocker - Alpha 1 and 2- blocker Alcohol, Caffeine (last 24hrs) Any type of cancer

Design outcomes

Primary

Measure	Time frame
The main objective will be to correlate endoscopic disease activity, measured by SES-CD, with (the change in) HRV.	—

Secondary

Measure	Time frame
As a second outcome we aim to investigate the Harvey Bradshaw index (HBI), serum CRP, white blood cells (WBC), faecal Calprotectin and urinary metanephrines in comparison to the HRV.	—

Countries

Netherlands

Outcome results