Down syndrome Trisomy 21
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: Patients: - Individuals with Down syndrome caused by an extra, not translocated copy of chromosome 21 - Age 0 - 1 yr Controls - Individuals without Down syndrome and a non-hereditary disorder fo which blood sampling is needed - Age 01- yr
Exclusion criteria
Exclusion criteria: Individual with Down syndrome with a major malformation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant differences in DNA-methylation- and genetranscription profiles between controls and DS individuals. | — |
Secondary
| Measure | Time frame |
|---|---|
| None. | — |
Countries
Netherlands
Outcome results
None listed