High density EMG investigation of stimulus-driven muscle responses associated with covert orienting

High density EMG investigation of stimulus-driven muscle responses associated with covert orienting - Fast muscle responses and freezing in Parkinson's disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON42546

Enrollment

Registered

2016-02-04

Start date

2017-01-12

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

parkinsonism Parkinson's disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: PD patients: A diagnosis of idiopathic PD Age between 45 and 70 year No musculoskeletal abnormalities of shoulder girdle and upper limbs Normal or corrected to normal vision;Control subjects: Age between 45 and 70 year No musculoskeletal abnormalities of shoulder girdle and upper limbs Normal or corrected to normal vision No neurological disease

Exclusion criteria

Exclusion criteria: Significant rest, postural or action tremor

Design outcomes

Primary

Measure	Time frame
The following parameters are evaluated: - Amplitude and timing of short-latency muscle response (SLR) in a time window of 50-150 ms after stimulus presentation - Suppression of EMG activity, in SLR time window, during orientation to ipsilateral side - Reaction times of manual responses to visual stimuli presented - Error rates for reaches and anti-reaches (towards and away from presented stimulus, respectively) - Correlations between SLR and behavioral measures	—

Measure

Time frame

The following parameters are evaluated: - Amplitude and timing of short-latency muscle response (SLR) in a time window of 50-150 ms after stimulus presentation - Suppression of EMG activity, in SLR time window, during orientation to ipsilateral side - Reaction times of manual responses to visual stimuli presented - Error rates for reaches and anti-reaches (towards and away from presented stimulus, respectively) - Correlations between SLR and behavioral measures

—

Secondary

Measure	Time frame
none	—

Countries

Netherlands

Outcome results