Respiratory signal driven breathing instructions to improve spatial alignment between respiratory gated PET and breath-hold CT

Respiratory signal driven breathing instructions to improve spatial alignment between respiratory gated PET and breath-hold CT - Breathing instructions in PET/CT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON42538

Enrollment

Registered

2015-07-23

Start date

2015-10-07

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer pulmonary carcinoma

Interventions

Twenty patients, will undergo a respiratory gated PET/CT protocol, consisting of a topogram, a low-dose CT and a respiratory gated PET scan. In addition a low-dose CT will be made with a respiratory

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with suspected lung malignancy, who will have a PET/CT scan.

Exclusion criteria

Exclusion criteria: Mentally incompetent

Design outcomes

Primary

Measure	Time frame
The mismatch between PET and CT measured for standard low-dose CT and PET, and breath-hold low-dose CT and PET for 1 anatomical location (lung-liver transition)	—

Secondary

Measure	Time frame
The mismatch between PET and CT measured for standard low-dose CT and PET and, breath hold low-dose CT and PET for lung lesions, measured by: • Mismatch between centroids of the lesions on PET and CT • Mismatch between lesions on PET and CT measured with the Jaccard similarity coefficient • Effect of attenuation correction of the CT on the PET reconstruction measured by the mean tracer uptake.	—

Measure

Time frame

The mismatch between PET and CT measured for standard low-dose CT and PET and, breath hold low-dose CT and PET for lung lesions, measured by: • Mismatch between centroids of the lesions on PET and CT • Mismatch between lesions on PET and CT measured with the Jaccard similarity coefficient • Effect of attenuation correction of the CT on the PET reconstruction measured by the mean tracer uptake.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)