normale processen van vertering en absorptie gastric emptying
Conditions
Interventions
Consumption of two different test meals, labeled with either 13C-acetate or
13C-octanoate, on 3 test days.
Meal 1: full-fat yogurt with sugar
Meal 2: pieces of boiled egg and a glass of chocolate mil
Sponsors
NIZO food research B.V.
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Age 18-35 years • Use of 3 meals per day • Voluntary participation (signed informed consent) • Willing to comply with study procedures • Accept disclosure of the financial benefit of participation in the study to the authorities concerned - Accept reporting of abnormal blood glucose values to volunteer or his/her physician
Exclusion criteria
Exclusion criteria: • Smoking • Current or previous underlying disease of the GI tract, liver, bile bladder, thyroid gland (self-reported) • Allergy to ingredients in the test products. • Use of antacids or laxatives (up till 1 month prior to inclusion) • Pregnancy and lactation • Vegetarians or vegans • Drug use • Personnel of NIZO food research, their partner and their first and second degree relatives • Participation in any clinical trial up to 30 days before Day 01 of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric emptying rate, based on 13CO2/12CO2 ratio in expired breath for up to 3 hours after meal consumption, and expressed as half-emptying time and lag phase. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other gastric emptying parameters: Gastric Emptying Coefficient Percentage Dose Recovery (PDR) Cumulative PDR Glucose concentration in finger prick blood | — |
Countries
Netherlands
Outcome results
None listed